Bibliometrics

The Brinkmann lab has collectively published more than 170 peer-reviewed scientific articles, books, and book chapters. Dr. Brinkmann has an h-index of 39, i10 index (articles cited > ten times) of 108, and more than 6,000 total citations (Google Scholar).

Dr. Brinkmann and his team have given or contributed to over 50 invited presentations, 150 conference platform presentations, and presented over 150 posters at scientific conferences across the world. The Brinkmann Lab is frequently one of the top contributing groups at international and regional meetings of the Society of Environmental Toxicology and Chemistry (SETAC) and the Canadian Ecotoxicity Workshop (CEW).

Research from the Brinkmann lab has been instrumental in informing policy on a variety of topics. For a detailed summary of our policy impact, check our SagePolicyProfiles page.

Books and Book Chapters

  • Seiler, T.B. & Brinkmann, M., editors (2022) In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems. Springer Protocols book series “Methods in Pharmacology and Toxicology”, Springer, Berlin/Heidelberg, Germany, ISSN: 1557-2153.
  • Brinkmann, M., Preuss, T.G., Hollert, H. (2016) Advancing In Vitro–In Vivo Extrapolations of Mechanism-Specific Toxicity Data Through Toxicokinetic Modeling. Book title: ‘In vitro Environmental Toxicology – Concepts, Application and Assessment’, Publisher: Springer International Publishing Switzerland, Editors: Reifferscheid, G., Buchinger, S.

Journal Articles

  • Hayati, F., Maslaki, S.A., Shirazi, M.M.A., Brinkmann, M., McPhedran, K.N. (2026) Photocatalytic degradation of the tire-derived chemical 1,3-Diphenylguanidine in stormwater using a biochar-supported N-Zn doped TiO2 catalyst. Chemical Engineering Journal.
  • Lin, J., Roberts, C., Kohlman, E., Jain, N., Amekor, M., Alcaraz, A.J., Wiseman, S., Hogan, N., Brinkmann, M., Hecker, M., 2026. Molecular Toxicity Pathways and Transcriptomic Points of Departure (tPODs) of 6PPD-Quinone in Early-Life Stage Lake Trout (Salvelinus namaycush). Environmental Science & Technology.
  • Seabrook, K.J., Adams, J.E., Robinson, S.A., Brinkmann, M., Brown, T.M., Challis, J.K., Chibwe, L., Marteinson, S., Philibert, D., Prosser, R.S., Orihel, D.M. (2026) A systematic map protocol to identify evidence for the environmental occurrence and toxic effects of the tire additive 6PPD. Environmental Evidence.
  • Bryshun, L., Hunnie, B., McPhedran, K., Brinkmann, M. (2025) Long-Term Leaching of 6PPD-Quinone from Recycled Rubber Mulch and Crumb in a Cold-Region Climate. Environmental Science & Technology Letters.
  • Seabrook, K.J., Winn, L.M., Brinkmann, M., Adams, J.E., Canete, A., Xie, L., Peng, H., Robinson, S.A., Orihel, D.M. (2025) First assessment of the ecotoxicological effects of the tire antioxidant 6PPD on early life stages of the popular sport fish species, the largemouth bass (Micropterus nigricans). Environmental Toxicology and Chemistry 44(11): 3225–3235.
  • Amekor, M., Kohlman, E., Roberts, C., Alcaraz, A., Jain, N., Al-Dissi, A., Hecker, M., Brinkmann, M., Hogan, N. (2025). Effects of legacy and emerging antimicrobial compounds to early-life stages of rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology 286: 107487.
  • Zeynali, R., Asadi, M., Ankley, P., Mahoney, H., Brinkmann, M., Acharya, B., McPhedran, K., Soltan, J. (2025). Smart municipal wastewater treatment sludge management: Enhancement of biogas production from anaerobic digestion amended by optimized sludge-derived biochar. Science of The Total Environment 989: 179860.
  • Bryshun, L.T., Hunnie, B., McPhedran, K.N., Brinkmann, M. (2025) Occurrence of the Tire-Derived Toxicant 6PPD-Quinone in Road Dust from Unpaved Roads in a Cold-Region Urban Area. Environmental Science & Technology Letters 12(9): 1247-1251.
  • Damdam, S., Hunnie, B., Jones, P., Hecker, M., Brinkmann, M., da Silva Junior, F.C. (2025) Toxicity assessment of 6PPD-quinone in human lung cells: Insights from BEAS-2B and A549 cell lines. Toxicology in Vitro 110: 106147
  • Woytowich, N., Roberts, C., Ankley, P., Brinkmann, M., Krogh, E., Duncan, K. (2025) Uncovering spatially resolved 6PPDQ metabolism in rainbow trout fry with nano-DESI mass spectrometry imaging. Environmental Science & Technology Letters 12(8): 937-944.
  • Challis, J.K., Cantin, J., Thresher, J., Curtis, A.W., Jones, P.D., Brinkmann, M., Hogan, N., Giesy, J.P., McAllister, T.A., Larney, F.J. (2025) Chemical and bioassay-based characterization of the growth promoter ractopamine in beef cattle manure. Environmental Toxicology and Chemistry: vgaf211.
  • Ankley, P., Mahoney, H., Brinkmann, M. (2025) Xenometabolomics in Ecotoxicology: Concepts and Applications. Environmental Science and Technology 59: 8308-8316.
  • Brinkmann, M., Embry, M., Curtis-Jackson, P., Laue, H., Franco, M. E., Schirmer, K., Sanders, G., Johanning, K. M. (2025) Is the Hyalella azteca Bioconcentration Test (HYBIT) currently fit for purpose? Environmental Toxicology and Chemistry 44: 1454–1456.
  • Ankley, P.J., Challis, J.K., Xia, P., Gong, Yufeng, Zhou, Y., Hecker, M., Giesy, J.P., Brinkmann, M. (2025) Interactions of erythromycin and an antibiotic mixture with the gut microbiome of juvenile rainbow trout. Chemosphere 377: 144263.
  • Alper, J.A., Murray, S., Ankley, P., Raes, K., Kurukulasuriya, S., Crump, D., Basu, N., Brinkmann, M., Hecker, M., Hogan, N. (2025) Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[a]pyrene in Early-Life-Stage Rainbow Trout. Environmental Science and Technology 59: 6971-6982.
  • Selinger, S., Montgomery, D., Wiseman, S., Hecker, M., Weber, L., Brinkmann, M., Janz, D. (2025) Acute cardiorespiratory effects of 6PPD-quinone on juvenile rainbow trout (Oncorhynchus mykiss) and Arctic char (Salvelinus alpinus). Aquatic Toxicology: 107288.
  • Woytowich, N., Roberts, C., Ankley, P., Brinkmann, M., Krogh, E., Duncan, K. (2025) Uncovering spatially resolved 6PPDQ metabolism in rainbow trout fry with nano-DESI mass spectrometry imaging. ChemRxiv: 1.
  • Roberts, C., Lin, J., Kohlman, E., Jain, N., Amekor, M., Alcaraz, A.J., Hogan, N., Hecker, M., Brinkmann, M. (2025) Acute and Subchronic Toxicity of 6PPD-Quinone to Early Life Stage Lake Trout (Salvelinus namaycush). Environmental Science & Technology: 59.
  • Selinger, S., Hunnie, B., Roberts, C., Amekor, M., Hogan, N., Wiseman, S., Hecker, M., Weber, L., Janz, D., Brinkmann, M. (2025) Sublethal 6PPD-quinone exposure impairs swimming performance and aerobic metabolism in juvenile lake trout (Salvelinus namaycush). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 294: 110166.
  • Zeynali, R., Asadi, M., Ankley, P., Esser, M., Brinkmann, M., Soltan, J., McPhedran, K. (2024) Sustainable enhancement of biogas production from a cold-region municipal wastewater anaerobic digestion process using optimized sludge-derived and commercial biochar additives. Journal of Cleaner Production: 478.
  • Cardenes Perez, A.S., Challis, J.K., Alcaraz, A.J., Ji, X., Valery Ramirez, A.V., Hecker, M., Brinkmann, M. (2024) Developing an Approach for Integrating Chemical Analysis and Transcriptional Changes to Assess Contaminants in Water, Sediment, and Fish. Environmental Toxicology and Chemistry 43: 2252-2273.
  • Mahoney, H., Ankley, P., Roberts, C., Lamb, A., Schultz, M., Yutong Z., Giesy J.P., Brinkmann, M. (2024) Unveiling the Molecular Effects of Replacement and Legacy PFASs: Transcriptomic Analysis of Zebrafish Embryos Reveals Surprising Similarities and Potencies. Environmental Science & Technology 58(42): 18554-18565.
  • Lewin, W.C., Suhring, R., Fries, E., Solomon, M., Brinkmann, M., Weltersbach, M.S., Strehlow, H.V., Freese, M. (2024) Soft plastic fishing lures as a potential source of chemical pollution – Chemical analyses, toxicological relevance, and anglers’ perspectives. Science of the Total Environment 946: 173884.
  • Mora-Solarte, D., Jimenez, R., Calderón-Delgado, I., Duarte-Ruiz, A., Brinkmann, M., Velasco-Santamaria, Y. (2024) Variability of Bile Baseline Excitation-emission Fluorescence of Two Tropical Freshwater Fish Species. Journal of Fluorescence: 1-15.
  • Asadi, M., Hamilton, D., Shomachuk, C., Oloye, F.F., De Lange, C., Liang, J., Xia, P., Osunla, C.A., Cantin, J., Mejia, E.M., Gregorchuk, S.J., Becker, M.G., Mangat, C., Brinkmann, M., Jones, P.D., Giesy, J.P., McPhedran, K.N. (2024) Assessment of Rapid and Conventional RT-qPCR-Based Systems for Wastewater Surveillance. ACS ES&T Water: 4(10).
  • Selinger, S., Montgomery, D., Wiseman, S., Hecker, M., Weber, L., Brinkmann, M., Janz, D. (2025) Acute cardiorespiratory effects of 6PPD-quinone on juvenile rainbow trout (Oncorhynchus mykiss) and Arctic char (Salvelinus alpinus). SSRN: 4956593.
  • Lari, E., Elahi, Z., Wong, J., Bluhm, K., Brinkmann, M., Goss, G. (2024) Impacts of UV light on the effects of either conventional or nano-enabled azoxystrobin on Daphnia magna. Chemosphere: 364.
  • Mahoney, H., da Silva, F., Brinkmann, M., Giesy, J.P. (2024) Mixtures of legacy and replacement perfluorosulphonic acids (PFSAs) demonstrate ratio-, concentration- and endpoint-dependent synergistic interactions in vitro. Chemosphere: 361.
  • Ankley, P.J., da Silva, F.C., Hunnie, B., Roberts, C., Eriksson, A.N.M., Kohlman, E., Corker, J., Westcott, J., Germain, B., Martin, M.J., Dubiel, J., Anderson-Bain, K., Urrutia, R.M., Hogan, N., Giesy, J.P., Wiseman, S., Krol, E., Hecker, M., Brinkmann, M. (2024) Xenometabolome of Early-Life Stage Salmonids Exposed to 6PPD-Quinone. bioRxiv: 2024.06. 12.598661.
  • Ankley, P.J., da Silva, F.C., Montgomery, D., Schultz, M., Krol, E., Hecker, M., Brinkmann, M. (2024) Biotransformation of 6PPD-quinone In Vitro Using RTL-W1 Cell Line. Environmental Science & Technology Letters 11(7): 687-693.
  • Roberts, C., Kohlman, E., Jain, N., Amekor, M., Alcaraz, A.J., Hogan, N., Brinkmann, M., Hecker, M. (2024) Subchronic and Acute Toxicity of 6PPD-Quinone to Early Life Stage Rainbow Trout (Oncorhynchus mykiss). Environmental Science & Technology 59: 6771-6777.
  • Ankley, P., Amekor, M., Kohlman, E., Roberts, C., Zhou, Y., Hecker, M., Giesy, J., Brinkmann, M., Hogan, N. (2024) Effects of Antimicrobial Exposure on the Gut Microbiome of Early-Life Stage Fish: A Chemical and Species Comparison. SSRN: 4763861.
  • Roberts, C., Kohlman, E., Jain, N., Amekor, M., Alcaraz, A.J., Hogan, N., Brinkmann, M., Hecker, M. (2024) Subchronic and Acute Toxicity of 6PPD-Quinone to Early Life Stage Rainbow Trout (Oncorhynchus mykiss). BioRxiv: 1.
  • Selinger, S.J., Hunnie, B., Roberts, C., Amekor, M., Hogan, N., Wiseman, S., Hecker, M., Weber, L.P., Janz, D., Brinkmann, M. (2024) Sublethal 6PPD-quinone exposure impairs swimming performance and aerobic metabolism in juvenile lake trout (Salvelinus namaycush). SSRN: 4955622.
  • Esser, M., Brinkmann, M., Hecker, M. (2024) Solving freshwater conservation challenges through next-generation sequencing approaches. Environmental Science: Advances: 3(9): 1181-1196.
  • Oloye, F.F., Asadi, M., Yusuf, W., Champredon, D., Pu, X., Femi-Oloye, O.P., De Lange, C., El-Baroudy, S., Osunla, C.A., Xie, Y., Cantin, J., McPhedran, K.N., Brinkmann, M., Servos, M.R., Jones, P.D., Giesy, J.P. (2024) Rapid Spread of Omicron Sub-Lineage as Evidence by Wastewater Surveillance. Water: 16(2): 318.
  • Oloye, F.F., Xie, Y., Challis, J.K., Femi-Oloye, O.P., Brinkmann, M., McPhedran, K.N., Jones, P.D., Servos, M.R., Giesy, J.P. (2023) Understanding common population markers for SARS-CoV-2 RNA normalization in wastewater–A review. Chemosphere: 138682.
  • Hecker, M., Peijnenburg, W., Lam, P.K. Brinkmann, M. (2023) Emerging issues in aquatic toxicology-Plastic pollution. Aquatic Toxicology 264: 106729.
  • Asadi, M., Hamilton, D., Shomachuk, C., Oloye, F.F., De Lange, C., Pu, X., Osunla, C.A., Cantin, J., El-Baroudy, S., Mejia, E.M., Gregorchuk, B., Michael G. Becker, M.G., Mangat, C., Brinkmann, M., Jones, P.D., Giesy, J.P., McPhedran, K.N. (2023) Assessment of rapid wastewater surveillance for determination of communicable disease spread in municipalities. Science of The Total Environment 901: 166541.
  • Montgomery, D., Ji, X., Cantin, J., Philibert, D., Foster, G., Selinger, S., Jain, N., Miller, J., McIntyre, J., de Jourdan, B., Wiseman, S., Hecker, M., Brinkmann, M. (2023) Interspecies Differences in 6PPD-Quinone Toxicity Across Seven Fish Species: Metabolite Identification and Semiquantification. Environmental Science & Technology 57(50): 21071-21079.
  • Oloye, F.F., Asadi, M., Yusuf, W., Champredon, D., Pu, X., Femi-Oloye, O.P., De Lange, C., El-Baroudy, S., Osunla, C.A., Xie, Y., Cantin, J., McPhedran, K.N., Brinkmann, M., Servos, M.R., Jones, P.D., Giesy, J.P.G. (2024) Rapid Spread of Omicron Sub-Lineage as Evidence by Wastewater Surveillance. Water 16(2): 318.
  • Esser, M., Ankley, P., Aubry-Wake, C., Xie, Y., Baulch, H., Hoggarth, C., Hecker, M., Hollert, H., Giesy, J.P., Pomeroy, J.W., Brinkmann, M., (2024) A preliminary investigation of microbial communities on the Athabasca Glacier within deposited organic matter. Environmental Science: Advances 3: 355-365.
  • Cheng, Y., Ding, J., Arenas, C.E.D., Brinkmann, M., Ji, X. (2024) A brief review on the assessment of potential joint effects of complex mixtures of contaminants in the environment. Environmental Science: Advances 3: 661-675.
  • Champredon, D., Becker, D., Peterson, S.W., Mejia, E., Hizon, N., Schertzer, A., Djebli, M., Oloye, F.F., Xie, Y., Asadi, M., Cantin, J., Pu, X., Osunla, C.A., Brinkmann, M., McPhedran, K.N., Servos, M.R., Giesy, J.P., Mangat, C. (2024) Emergence and spread of SARS-CoV-2 variants of concern in Canada: a retrospective analysis from clinical and wastewater data. BMC Infectious Diseases 24(1): 139.
  • Green, D., Bluhm, K., Brinkmann, M., Raes, K., Lane, T., Liber, K., Janz, D.M., Hecker, M. (2024) Cross-species apical microinjected selenomethionine toxicity in embryo-larval fishes. Science of The Total Environment 912: 169338.
  • Roberts, C., Lin, J., Kohlman, E., Jain, N., Amekor, M., Alcaraz, A.J., Hogan, N., Hecker, M., Brinkmann, M. (2024) Acute and sub-chronic toxicity of 6PPD-quinone to early-life stage lake trout (Salvelinus namaycush). bioRxiv: 2024-03.
  • Oloye, F.F., Xie, Y., Asadi, M., Challis, J.K., Osunla, C.A., Xia, P., Cantin, J., Femi-Oloye, O.P., Brinkmann, M., McPhedran, K.N., Sadowski, M. (2024) Solid-liquid distribution of SARS-CoV-2 in primary effluent of a wastewater treatment plant. MethodsX 12: 102645.
  • Zoroufchi Benis, K., Behnami, A., Minaei, S., Brinkmann, M., McPhedran, K.N., Soltan, J. (2023) Environmental occurrence and toxicity of 6PPD quinone, an emerging tire rubber-derived chemical: a review. Environmental Science & Technology Letters 10(10): 815-823.
  • Anderson-Bain, K., Roberts, C., Kohlman, E., Ji, X., Alcaraz, A.J., Miller, J., Gangur-Powell, T., Weber, L., Janz, D., Hecker, M., Montina, T., Brinkmann, M., Wiseman, S. (2023) Apical and mechanistic effects of 6PPD-quinone on different life-stages of the fathead minnow (Pimephales promelas). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 271: 109697.
  • Brinkmann, M., Petersen, S., Pelletier, A., Bryshun, L., Schaefer, N., Barnes, M., Doig, L., Strickert, G., Jardine, T. (2024) Multiple lines of evidence to assess risk from dioxins and dioxin-like chemicals in sediment and fish from waterbodies along a large prairie river. Journal of Soils and Sediments 24(1): 414-424.
  • Botelho, M.T., Militão, G.G., Brinkmann, M., Umbuzeiro, G.D.A. (2023) Toxicity and mutagenicity studies of 6PPD‐quinone in a marine invertebrate species and bacteria. Environmental and Molecular Mutagenesis 64(6): 335-341.
  • Horn, M., Brinkmann, M., Machtaler, S. (2023) Contrast-enhanced ultrasound imaging for assessment of intestinal inflammation in rainbow trout. Comparative Biochemistry and Physiology, Part C., http://dx.doi.org/10.2139/ssrn.4327161.
  • Morrisey, C., Fritsch, C., Fremlin, K., Adams, W., Borga, K., Brinkmann, M., Eulaers, I., Gobas, F., Moore, D., van den Brink, N., Wickwire, T. (2023) Advancing exposure assessment approaches to improve wildlife risk assessment. Integrated Environmental Assessment and Management, https://doi.org/10.1002/ieam.4743.
  • Ji, X., Arenas, C.E.D., Perez, A., Giesy, J.P., Brinkmann, M. (2023) Predicting kinetics of resupply of organic pollutants from sediments, using diffusive gradients in thin films (DGT) samplers and their bioavailability to aquatic invertebrates. Environmental Toxicology and Chemistry, https://doi.org/10.1002/etc.5681.
  • Asadi, M., Oloye, F., Xie, Y., Cantin, J., Challis, J.K., McPhedran, K.N., Yusuf, W., Champedron, D., Xia, P., De Lange, C., El-Badoury, S., Servos, M., Jones, P.D., Giesy, J.P., Brinkmann, M. (2023) A wastewater-based risk index for SARS-CoV-2 infections among three cities on the Canadian Prairie. Science of the Total Environment, 876, 162800.
  • Kumayon, I., Prajapati, S., Brinkmann, M., Kahan, T. (2023) Levels and composition of microplastics and microfibers in the South Saskatchewan River and stormwater retention ponds in the City of Saskatoon, Canada. Environmental Science and Pollution Research, https://doi.org/10.21203/rs.3.rs-2890854/v1
  • Esser, M., Hoggarth, C., Baulch, H., Challis, J.K., Xie, Y., Giesy, J.P., Hecker, M., Brinkmann, M. (2023) Wastewater discharges alter microbial community composition in surface waters of the Canadian prairies. Chemosphere 334, 138991.
  • Prajapati, S., Sabokruhie, P., Brinkmann, M., Lindenschmidt, K.E. (2023). Modelling Transport and Fate of Copper and Nickel across the South Saskatchewan River Using WASP—TOXI. Water 15, 265.
  • Malala Irugal Bandaralage, S., Bertucci, J.I., Park, B., Green, D., Brinkmann, M., Masse A, Crump, D., Basu, N., Hogan, N., Hecker, M. (2023). Maternal Transfer and Apical and Physiological Effects of Dietary Hexabromocyclododecane Exposure in Parental Fathead Minnows (Pimephales promelas). Environmental Toxicology and Chemistry 42, 143-153.
  • Mahoney, H., Cantin, J., Rybchuk, J., Xie, Y., Giesy, J.P., Brinkmann, M. (2023). Acute Exposure of Zebrafish (Danio rerio) to the Next-Generation Perfluoroalkyl Substance, Perfluoroethylcyclohexanesulfonate, Shows Similar Effects as Legacy Substances. Environmental Science and Technology 57, 4199-4207.
  • Mahoney, H., Cantin, J., Xie, Y., Brinkmann, M., Giesy, J.P. (2023). Perfluoroethylcyclohexane Sulphonate, an Emerging Perfluoroalkyl Substance, Disrupts Mitochondrial Membranes and the Expression of Key Molecular Targets in Vitro. Aquatic Toxicology 257, 106453.
  • Horn, M.E., Segner, H., Brinkmann, M., Machtaler, S. (2023). Chemically-induced trout model of acute intestinal inflammation using TNBS. Fish and Shellfish Immunology Reports 4, 100073.
  • Bourgeois, Z.M., Comfort, J., Schultz, M., Challis, J.K., Cantin, J., Ji, X., Giesy, J.P., Brinkmann, M. (2022) Predicting Hepatic Clearance of Psychotropic Drugs in Isolated Perfused Fish Livers Using a Combination of Two In Vitro Assays. Environmental Science & Technology 56(22): 15839-15847.
  • Challis, J.K., Popick, H., Harder, P., Giesy, J.P., McPhedran, K., Brinkmann, M. (2022) Occurrences of Tire Rubber-Derived Contaminants in Cold-Climate Urban Runoff. Environmental Science & Technology Letters 8(11): 961-967.
  • Ji, X., Cantin, J., Perez, A.S.C., Gong, Y., Giesy, J.P., Brinkmann, M. (2022) Combining passive sampling with fraction transfer and toxicokinetic modeling to assess bioavailability of organic pollutants in a benthic invertebrate, Lumbriculus variegatus. Journal of Hazardous Materials 441: 129986.
  • Jain, N., Hamilton, D., Mital, S., Ilias, A., Brinkmann, M., McPhedran, K. (2022) Long-term passive wastewater surveillance of SARS-CoV-2 for seven university dormitories in comparison to municipal surveillance. Science of the Total Environment 852: 158421.
  • Perez, A.S.C., Challis, J.K., Ji, X., Giesy, J.P., Brinkmann, M. (2022) Impacts of wastewater effluents and seasonal trends on levels of antipsychotic pharmaceuticals in water and sediments from two cold-region rivers. Science of the Total Environment 851: 158247.
  • Prajapati, S., Challis, J.K., Jardine, T.D., Brinkmann, M. (2022) Levels of pesticides and trace metals in water, sediment, and fish of a large, agriculturally-dominated river. Chemosphere 308: 136236.
  • El-Sherif, D.M., Eloffy, M.G., Elmesery, A., Abouzid, M., Gad, M., El-Seedi, H.R., Brinkmann, M., Wang, K., Al Naggar, Y. (2022) Environmental risk, toxicity, and biodegradation of polyethylene: a review. Environmental Science and Pollution Research, 1-17.
  • Oloye, F., Xie, Y., Asadi, M., Cantin, J., Challis, J.K., Brinkmann, M., McPhedran., K., Kristian, K., Keller, M., Sadowski, M., Jones, P.D., Landgraff, C., Mangat, C., Fuzzen, M., Servos, M.R., Giesy, J.P. (2022) Rapid transition between SARS-CoV-2 variants of concern Delta and Omicron detected by monitoring municipal wastewater from three Canadian cities. Science of the Total Environment 841: 156741.
  • Schultz, M., Krause, S., Brinkmann, M. (2022) Validation of Methods for in Vitro–in Vivo Extrapolation Using Hepatic Clearance Measurements in Isolated Perfused Fish Livers. Environmental Science & Technology 56: 12416-12423.
  • Mahoney, H., da Silva Junior, F.C., Roberts, C., Schultz, M., Ji, X., Alcaraz, A.J., Montgomery, D., Selinger, S., Challis, J.K., Giesy, J.P., Weber, L., Janz, D., Wiseman, S., Hecker, M., Brinkmann, M. (2022) Exposure to the Tire Rubber-Derived Contaminant 6PPD-Quinone Causes Mitochondrial Dysfunction In Vitro. Environmental Science & Technology Letters 9: 765-771.
  • Mahoney, H., Xie, Y., Brinkmann, M., Giesy, J.P. (2022) Next Generation Per-and Poly-Fluoroalkyl Substances: Status and Trends, Aquatic Toxicity, and Risk Assessment. Eco-Environment & Health 1: 117-131.
  • Ji, X., Challis, J.K., Cantin, J., Cardenas Perez, A., Gong, Y., Giesy, J.P., Brinkmann, M. (2022) A novel passive sampling and sequential extraction approach to investigate desorption kinetics of emerging organic contaminants at the sediment-water interface. Water Research, 118455.
  • Popick, H., Brinkmann, M., McPhedran, K. (2022) Assessment of stormwater discharge contamination and toxicity for a cold-climate urban landscape. Environmental Sciences Europe, 34: 43.
  • Ji, X., Challis, J.K., Cantin, J., Cardenas Perez, A.S., Gong, Y., Giesy, J.P., Brinkmann, M. (2022) Desorption kinetics of antipsychotic drugs from sandy sediments by diffusive gradients in thin-films technique. Science of the Total Environment, 155104.
  • Ankley, P., Graves, S., Xie, Y., DeBofsky, A., Weber, A., Brinkmann, M., Palace, V., Liber, K., Hecker, M., Janz, D., Giesy, J.P. (2022) Effects of in situ experimental selenium exposure on finescale dace (Phoxinus neogaeus) gut microbiome. Environmental Research, 113151.
  • Miller, J., Brinkmann, M., Raza, Y., Dubiel, J., Fujita, K., Doering, J., Wiseman, S. (2022) Inhibition of Oocyte Maturation by Malathion and Structurally Related Chemicals in Zebrafish (Danio rerio) After In Vitro and In Vivo Exposure. Environmental Toxicology and Chemistry, in press.
  • Brinkmann, M., Montgomery, D., Selinger, S., Miller, J.G.P., Stock, E., Alcaraz, A.J., Challis, J.K., Weber, L., Janz, D., Hecker, M., Wiseman, S. (2022) Acute toxicity of the tire rubber-derived chemical 6PPD-quinone to four fishes of commercial, cultural, and ecological importance. Environmental Science and Technology Letters 9: 333-338.
  • Xie, Y., Challis, J.K., Oloye, F., Asadi, M., Cantin, J., Brinkmann, M., McPhedran, K.N., Hogan, N., Sadowski, M., Jones, P.D., Landgraff, C., Mangat, C., Servos, M.R., Giesy, J.P. (2022) RNA in Municipal Wastewater Reveals Magnitudes of COVID-19 Outbreaks across Four Waves Driven by SARS-CoV-2 Variants of Concern. Environmental Science and Technology Water, https://doi.org/10.1021/acsestwater.1c00349.
  • Al Masum, M., Popick, H., Brinkmann, M., Hecker, M., McPhedran, K. (2022) Urban stormwater runoff pollutant loadings: GIS land use classification vs. sample-based predictions Environmental Science and Pollution Research, https://doi.org/10.1007/s11356-022-18876-x.
  • Kinar, N.J. and Brinkmann, M. (2022) Development of a sensor and measurement platform for water quality observations: design, sensor integration, 3D printing and open source hardware. Environmental Monitoring and Assessment 194: 207.
  • Popick, H., Brinkmann, M., McPhedran, K. (2022) Traffic‑derived contaminant loading in snow storage facilities during spring melt. Environmental Science and Pollution Research, https://doi.org/10.1007/s11356-021-18340-2.
  • Fuchylo, U., Alharbi, H., Alcaraz, A.J.G., Jones, P., Giesy, J.P., Hecker, M., Brinkmann, M. (2022) Inflammation of gill epithelia in fish causes increased permeation of petrogenic polar organic chemicals via disruption of tight junctions. Environmental Science and Technology 56: 1820-1829.
  • Alcaraz, A.J.G., Baraniuk, S., Mikulášek, K., Park, B., Lane, T., Burbridge, C., Ewald, J., Potěšil, D., Xia, J., Zdráhal, Z., Schneider, D., Crump, D., Basu, N., Hogan, N., Brinkmann, M., Hecker, M. (2021) Comparative analysis of transcriptomic points-of-departure (tPODs) and apical responses in embryo-larval fathead minnows exposed to fluoxetine. Environmental Pollution, 118667.
  • Doering, J.A., Brinkmann, M., Lucio, M., Stoeck, S., Vien, A., Petersen, S., Rhen, T., Jones, P.D., Hecker, M., Schroeder, A. (2022) Sensitivity of a model reptile, the common snapping turtle (Chelydra serpentina), to in ovo exposure to TCDD and other dioxin-like chemicals. Environmental Toxicology and Chemistry 41: 175-183.
  • Ji, X., Challis, J.K., Brinkmann, M. (2021) A critical review of diffusive gradients in thin films technique for measuring organic pollutants: Potential limitations, application to solid phases, and combination with bioassays. Chemosphere 287, 132352.
  • DeBofsky, A., Xie, Y., Challis, J.K., Ankley, P.J., Brinkmann, M., Jones, P.D., John P. Giesy, J.P. (2021) 16S rRNA metabarcoding unearths responses of rare gut microbiome of fathead minnows exposed to benzo[a]pyrene. Science of The Total Environment, 151060. Journal
  • Schmitz, M., Deutschmann, B., Markert, N., Backhaus, T., Brack, W., Brauns, M., Brinkmann, M., Hollert, H. (2021) Demonstration of an aggregated biomarker response approach to assess the impact of point and diffuse contaminant sources in feral fish in a small river case study. Science of The Total Environment, 150020.
  • Crawford, S. E., Brinkmann, M., Ouellet, J. D., Lehmkuhl, F., Reicherter, K., Schwarzbauer, J., Hollert, H. (2021). Remobilization of pollutants during extreme flood events poses severe risks to human and environmental health. Journal of Hazardous Materials, 126691.
  • Grimard, C., Mangold-Döring, A., Alharbi, H., Weber, L., Hogan, N., Jones, P., Giesy, J., Hecker, M., Brinkmann, M. (accepted) Toxicokinetic models for uptake and biotransformation of organic contaminants in two life stages of white sturgeon (Acipenser transmontanus). Environmental Science and Technology.
  • Mangold-Döring, A., Grimard, C., Green, D., Petersen, S., Nichols, J., Hogan, N., Weber, L., Hollert, H., Hecker, M., Brinkmann, M. (2021) A Novel Multi-Species Toxicokinetic Modeling Approach in Support of Chemical Risk Assessment. Environmental Science and Technology.
  • Al Naggar, Y., Brinkmann, M., Sayes, C.M., AL-Kahtani, S.N., Dar, S.A., El-Seedi, H.R., Grünewald, B., Giesy, J.P. (2021) Are Honey Bees at Risk from Microplastics? Toxics 2021, 9, 109.
  • DeBofsky, A., Xie, Y., Challis, J.K., Jain, N., Brinkmann, M., Jones, P.D., Giesy, J.P. (2021) Responses of juvenile fathead minnow (Pimephales promelas) gut microbiome to a chronic dietary exposure of benzo[a]pyrene. Environmental Pollution 278, 116821.
  • Alcaraz, A.J., Potěšil, D., Mikulášek, K., Green, D., Park, B., Burbridge, C., Bluhm, K., Soufan, O., Lane, T., Pipal, M., Brinkmann, M., Xia, J., Zdráhal, Z., Schneider, D., Crump, D., Basu, N., Hogan, N., Hecker, M. (2021) Development of a Comprehensive Toxicity Pathway Model for 17α-Ethinylestradiol in Early Life Stage Fathead Minnows (Pimephales promelas). Environmental Science and Technology, https://doi.org/10.1021/acs.est.0c05942.
  • Everitt, S., Fujita, K.K., MacPherson, S., Brinkmann, M., Pyle, G.G., Wiseman, S. (2021) Toxicity of Weathered Sediment-Bound Dilbit to Early Life Stages of Zebrafish (Danio rerio). Environmental Science and Technology 55: 1721-1729.
  • Prajapati, S., Beal, M., Maley, J., Brinkmann, M. (2021) Qualitative and quantitative analysis of microplastic contamination in effluents of the City of Saskatoon wastewater treatment plant. Environmental Science and Pollution Research, https://doi.org/10.1007/s11356-021-12898-7.
  • Goncin, U., Ton, N., Reddy, A., El Kaffas, A., Brinkmann, M., Machtaler, S. (2021) Contrast-enhanced ultrasound imaging for assessing liver perfusion in rainbow trout. Science of The Total Environment 750, 141231.
  • Müller, A.-K., Markert, N., Leser, K., Kämpfer, D., Schiwy, S., Riegraf, C., Gan, L. Abdallah, A.T., Denecke, B., Segner, H., Crawford, S.E., Brinkmann, M., Hollert, H. (2021) Bioavailability and impacts of estrogenic compounds from suspended sediment on rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology 231, 105719.
  • Shekh, K., Saeed, H., Kodzhahinchev, V., Brinkmann, M., Hecker, M., Niyogi, S. (2020). Differences in the subcellular distribution of cadmium and copper in the gills and liver of white sturgeon (Acipenser transmontanus) and rainbow trout (Oncorhynchus mykiss). Chemosphere, 265, 129142.
  • Brinkmann, M., Ouellet, J.D., Zennegg, M., Buchinger, S., Reifferscheid, G., Hollert, H. (2020) Combined sediment desorption and bioconcentration model to predict levels of dioxin-like chemicals in fish. Science of the Total Environment 758, 143891.
  • Everitt, S., MacPherson, S., Brinkmann, M., Wiseman, S., Pyle, G. (2020) Effects of weathered sediment-bound dilbit on freshwater amphipods (Hyalella azteca). Aquatic Toxicology 228, 105630.
  • Grimard, C., Mangold-Döring, A., Schmitz, M., Alharabi, H., Jones, P.D., Giesy, J.P., Hecker, M., Brinkmann, M. (2020) In vitro-in vivo and cross-life stage extrapolation of uptake and biotransformation of benzo[a]pyrene in the fathead minnow (Pimephales promelas). Aquatic Toxicology 228, 105616.
  • Westhaus, S., Weber, F. A., Schiwy, S., Linnemann, V., Brinkmann, M., Widera, M., … & Ciesek, S. (2020) Detection of SARS-CoV-2 in raw and treated wastewater in Germany–Suitability for COVID-19 surveillance and potential transmission risks. Science of The Total Environment 751: 141750.
  • Brinkmann, M., Alharbi, H., Fuchylo, U., Wiseman, S., Morandi, G., Peng, H., Giesy, J.P., Jones, P.D., Hecker, M. (2020) Mechanisms of pH-dependent uptake of ionizable organic chemicals by fish from oil sands process-affected water (OSPW). Environmental Science and Technology, 54: 9547-9555.
  • Ouellet, J., Gembé, C., Buchinger, S., Reifferscheid, G., Hollert, H., Brinkmann, M. (2020) Validation of the micro-EROD assay with H4IIE cells for assessing sediment contamination with dioxin-like chemicals. Environmental Pollution 265: 114984.
  • DeBofsky, A., Xie, Y, Grimard, C., Alcaraz, A.J., Brinkmann, M., Hecker, M., Giesy, J.P. (2020) Differential responses of gut microbiota of male and female fathead minnow (Pimephales promelas) to a short-term environmentally-relevant, aqueous exposure to benzo[a]pyrene. Chemosphere 252: 126461.
  • Schiwy, S., Herber, A.K., Hollert, H., Brinkmann, M. (2020) New Insights into the Toxicokinetics of 3,4-Dichloroaniline in Early Life Stages of Zebrafish (Danio rerio). Toxics 8: 16.
  • Freese, M., Rizzo, L., Pohlmann, J.-D., Marohn, L., Witten, P.E., Gremse, F. Rütten, S., Güvener, N., Michael, S., Wysujack, K., Lammers, T., Kiessling, F., Hollert, H., Hanel, R., Brinkmann, M. (2019) Bone resorption and body reorganization during maturation induce maternal transfer of toxic metals in anguillid eels. Proceedings of the National Academy of Sciences of America (PNAS) 116: 11339-11344.
  • Brinkmann, M., Schneider, A.L., Bluhm, K., Schiwy, S., Lehmann, G., Deutschmann, B., Müller, A., Tiehm, A., Hollert, H. (2019) Ecotoxicity of NSO‐heterocycles (NSO‐HET) and short‐chained alkyl phenols (SCAP) commonly detected in contaminated groundwater. Environmental Toxicology and Chemistry 38: 1343-1355.
  • Brinkmann, M., Barz, B., Carrière, D., Velki, M., Smith, K., Meyer-Alert, H., Müller, Y., Thalmann, B., Bluhm, K., Schiwy, S. (2019) Bioactivation of quinolines in a recombinant estrogen receptor transactivation assay is catalyzed by N-methyltransferases. Chemical Research in Toxicology 32: 698-707.
  • Deutschmann, B., Müller, A.K., Hollert, H., Brinkmann, M. (2019) Assessing the fate of brown trout (Salmo trutta) environmental DNA in a natural stream using a sensitive and specific dual-labelled probe. Science of The Total Environment 655: 321-327.
  • Hollert, H., Crawford, S., Brack, W., Brinkmann, M., Fischer, E., Hartmann, K., Keiter, S., Ottermanns, R., Ouellet, J., Rinke, K., Rösch, M., Ross,-Nickoll, M., Schäffer, A., Schuth, C., Schulze, T., Schwarz, A., Seiler, T.-B., Wessels, M., Hinderer, M., Schwalb, A. (2018) Looking back – Looking forward: A novel multi-time slice weight-of-evidence approach for defining reference conditions to assess the impact of human activities on lake systems. Science of the Total Environment 626: 1036-1046.
  • Apenova, N., Peng, H., Hecker, M., Brinkmann, M. (2018) A rapid and sensitive fluorometric method for determination of aldehyde oxidase activity. Toxicology and Applied Pharmacology 341: 30-37.
  • Brinkmann, M., Hecker, M., Giesy, J.P., Jones, P.D., Ratte, H.T., Hollert, H., Preuss, T.G. (2018) Generalized concentration addition accurately predicts estrogenic potentials of mixtures and environmental samples containing partial agonists. Toxicology in Vitro 46: 294-303.
  • Eichbaum, K., Brinkmann, M., Nuesser, L., Gembé, C., Ohlig, M., Buchinger, S., Reifferscheid, G., Hecker, M., Giesy, J.P., Hollert, H. (2018) In vitro tools for the toxicological evaluation of sediments and dredged materials: intra- and inter-laboratory comparisons of chemical and bioanalytical methods. Environmental Science and Pollution Research 25: 4037-4050.
  • Crawford, S. E., Cofalla, C, Aumeier, B., Brinkmann, M., Classen, E., Esser, V., Ganal, C., Kaip, E., Häussling, R., Lehmkuhl, F., Letmathe, P., Müller, A.-K., Rabinovitch, I., Reicherter, K., Schwarzbauer, J., Schmitt, M., Stauch, G., Wessling, M., Yüce, S., Hecker, M., Kidd, K. A., Altenburger, R., Brack, W., Schüttrumpf, H., Hollert, H. (2017) Project house water: a novel interdisciplinary framework to assess the environmental and socioeconomic consequences of flood-related impacts. Environmental Sciences Europe 29: 23.
  • Steffens, S., Nüßer, L., Seiler, T.-B., Ruchter, N., Schumann, M., Döring, R., Cofalla, C., Ostfeld, A., Salomons, E., Schüttrumpf, H., Hollert, H., Brinkmann, M. (2017) A versatile and low-cost open source pipetting robot for automation of toxicological and ecotoxicological bioassays. PLoS ONE 12(6): e0179636.
  • Koch, J., Bui, T., Lundström Belleza, E., Brinkmann, M., Hollert, H., Breitholtz, M. (2017) Temperature and food quantity effects on the harpacticoid copepod Nitocra spinipes: Combining in vivo bioassays with population modeling. PLoS ONE 12(3): e0174384.
  • Xiao, H. & Brinkmann, M., Thalmann, B., Schiwy, A., Große, B.S., Achten, C., Eichbaum, K., Gembé, C., Seiler, T., Hollert, H. (2017) Towards Streamlined Identification of Dioxin-like Compounds in Environmental Samples through Integration of Suspension Bioassay. Environmental Science & Technology 51: 3382-3390.
  • Brack, W., Dulio, V., Ågerstrand, M., Allan, I., Altenburger, R., Brinkmann, M., Bunke, D., Burgess, R.M., Cousins, I., Escher, B.I., Hernández, F.J., Hewitt, L.M., Hilscherová, K., Hollender, J., Hollert, H., Kase, R.,Klauer, B., Lindim, C., López Herráeza, D., Miègen, C., Munthe, J., O’Toole, S., Posthuma, L., Rüdel, H., Schäfer, R.B., Sengl, M., Smedes, F., van deMeent, D., van den Brink, P.J., van Gils, J., van Wezel, A.P., Vethaak, A.D., Vermeirssen, E., von der Ohe, P.C., Vrana, B. (2017) Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources. Science of the Total Environment 576: 720–737.
  • Koglin, S., Kammann, U., Eichbaum, K., Reininghaus, M., Eisner, B., Wiseman, S., Hecker, M., Buchinger, S., Reifferscheid, G., Hollert, H., Brinkmann, M. (2016) Toward understanding the impacts of sediment contamination on a native fish species: transcriptional effects, EROD activity, and biliary PAH metabolites. Environmental Sciences Europe 28:28.
  • Xiao, H., Krauss, M., Floehr, T., Yan, Y., Bahlmann, A., Eichbaum, K., Brinkmann, M., Zhang, X., Yuan, X., Brack, W., Hollert, H. (2016) Effect-directed analysis of aryl hydrocarbon receptor agonists in sediments from the Three Gorges Reservoir, China. Environmental Science & Technology 50: 11319-11328.
  • Werner, I., Aldrich, A., Becker, B., Becker, D., Brinkmann, M., Burkhardt, M., Caspers, N., Campiche, S., Chèvre, N., Düring, R.-A., Escher, B.I., Fischer, F., Giebner, S., Heye, K., Hollert, H., Junghans, M., Kienle, C., Knauer, K., Korkaric, M., Märkl, V., Muncke, J., Oehlmann, J., Reifferscheid, G., Rensch, D., Schäffer, A., Schiwy, S., Schwarz, S., Segner, H., Simon, E., Triebskorn, R., Vermeirssen, E.L.M., Wintgens, T., Zennegg, M. (2016) The 2015 Annual Meeting of SETAC German Language Branch in Zurich (7–10 September, 2015): Ecotoxicology and environmental chemistry—from research to application. Environmental Sciences Europe 28, 1-12.
  • Michel, N., Freese, M., Brinkmann, M., Pohlmann, J.-D., Hollert, H., Kammann, U., Haarich, M., Theobald, N., Gerwinski, W., Rotard, W., Hanel, R. (2016) Fipronil and two of its transformation products in water and European eel from the river Elbe. Science of the Total Environment 568: 171-179.
  • Förstner, U., Hollert, H., Brinkmann, M., Eichbaum, K., Weber, R., Salomons, W. (2016) Dioxin in the Elbe river basin: policy and science under the water framework directive 2000–2015 and toward 2021. Environmental Sciences Europe 28: 9.
  • Eichbaum, K., Brinkmann, M., Nuesser, L., Buchinger, S., Reifferscheid, G., Codling, G., Jones, P., Giesy, J.P., Hecker, M., Hollert, H. (2016) Bio-analytical and instrumental screening of the uptake of sediment-borne, dioxin-like compounds in roach (Rutilus rutilus). Environmental Science and Pollution Research 23: 12060-12074.
  • Brinkmann, M., Schlechtriem, C., Reininghaus, M., Eichbaum, K., Buchinger, S., Reifferscheid, G., Hollert, H., Preuss, T.G. (2016) Cross-Species Extrapolation of Uptake and Disposition of Neutral Organic Chemicals in Fish Using a Multispecies Physiologically-Based Toxicokinetic Model Framework. Environmental Science and Technology 50: 1914–1923.
  • Brinkmann, M. & Rizzo, L.Y., Lammers, T., Gremse, F., Schiwy, S., Kiessling, F., Hollert, H. (2016) Micro-computed tomography (μCT) as a novel method in ecotoxicology — determination of morphometric and somatic data in rainbow trout (Oncorhynchus mykiss). Science of the Total Environment 543: 135-139.
  • Brinkmann, M. & Koglin, S., Eisner, B., Wiseman, S., Hecker, M., Eichbaum, K., Thalmann, B., Buchinger, S., Reifferscheid, G., Hollert, H. (2016) Characterization of transcriptional responses to dioxins and dioxin-like contaminants in roach (Rutilus rutilus) using whole transcriptome analysis. Science of the Total Environment 541: 412-423.
  • Schulze-Sylvester, M., Heimann, W., Maletz, S., Seiler, T.-B., Brinkmann, M., Zielke, H., Schulz, R., Hollert, H. (2015) Are sediments a risk? An ecotoxicological assessment of sediments from a quarry pond of the Upper Rhine River. Journal of Soils and Sediments 16: 1069–1080
  • Schiwy, A. & Brinkmann, M., Thiem, I., Guder, G., Winkens, K., Eichbaum, K., Nüßer, L., Thalmann, B., Buchinger, S., Reifferscheid, G., Seiler, T.-B., Thoms, B., Hollert, H. (2015) Determination of the dioxin-like potential of single substances, complex mixtures and environmental samples in the Micro-EROD assay with H4IIE cells. Nature Protocols 10: 1728–1741.
  • Brinkmann, M., Eichbaum, K., Reininghaus, M., Koglin, S., Kammann, U., Baumann, L., Segner, H., Zennegg, M., Buchinger, S., Reifferscheid, G., Hollert, H. (2015) Towards science-based sediment quality standards for dioxin-like compounds – effects of field-collected sediments in rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology 166: 50-62.
  • Brinkmann, M. & Freese, M. & Pohlmann, J.-D., Kammann, U., Preuss, T.G., Buchinger, S., Reifferscheid, G., Beiermeister, A., Hanel, R., Hollert, H. (2015): A physiologically based toxicokinetic (PBTK) model for moderately hydrophobic organic chemicals in the European eel (Anguilla anguilla). Science of the Total Environment 536: 279-287.
  • Müller, A.-K., Brinkmann, M., Baumann, L., Stoffel, M.H., Segner, H., Kidd, K.A., Hollert, H. (2015) Morphological Alterations in the Liver of Yellow Perch (Perca flavescens) from a Biological Mercury Hotspot. Environmental Science and Pollution Research 22: 17330–17342.
  • Brinkmann, M., Floehr, T., Xiao, H., Roß-Nickoll, M., Schäffer, A., Hollert, H. (2015) Wasserforschung gestern und heute: Integrierte Bewertung von Gewässern und Sedimenten im deutsch-chinesischen Kontext. Bulletin of the German China Association 58: 34-41.
  • Lundström-Belleza, E., Brinkmann, M., Preuss, T.G., Breitholtz, M. (2014) Population-level effects in Amphiascus tenuiremis: Contrasting matrix- and individual-based population models. Aquatic Toxicology 157: 207–214.
  • Eichbaum, K., Brinkmann, M., Buchinger, S., Reifferscheid, G., Hecker, M., Giesy, J.P., Engwall, M., van Bavel, B., Hollert, H. (2014) In vitro bioassays for detecting dioxin-like activity — Application potentials and limits of detection, a review. Science of the Total Environment 487: 37-48.
  • Brinkmann, M. & Maletz, S.X., Krauss, M., Bluhm, K., Schiwy, S., Kuckelkorn, J., Tiehm, A., Brack, W., Hollert, H. (2014) Heterocyclic aromatic hydrocarbons show estrogenic activity upon metabolization in a recombinant transactivation assay. Environmental Science and Technology 48: 5892–5901.
  • Hollert, H., Brinkmann, M., Hudjetz, S., Cofalla, C., Schüttrumpf, H. (2014). Hochwasser–ein unterschätztes Risiko. Biologie in unserer Zeit, 44(1), 44-51.
  • Brinkmann, M., Eichbaum, K., Kammann, U., Hudjetz, S., Cofalla, C., Buchinger, S., Reifferscheid, G., Schüttrumpf, H., Preuss, T., Hollert, H. (2014) Physiologically-based toxicokinetic models help identifying the key factors affecting contaminant uptake during flood events. Aquatic Toxicology 152: 38-46.
  • Brinkmann, M., Eichbaum, K., Buchinger, S., Reifferscheid, G., Bui, T., Schaeffer, A., Hollert, H., Preuss, T.G. (2014) Understanding receptor-mediated effects in rainbow trout: in vitro-in vivo extrapolation using physiologically based toxicokinetic models. Environmental Science and Technology 48: 3303-3309.
  • Brinkmann, M., Blenkle, H., Salowsky, H., Bluhm, K., Schiwy, S., Tiehm, A., Hollert, H. (2014) Genotoxicity of Heterocyclic PAHs in the Micronucleus Assay with the Fish Liver Cell Line RTL-W1. PLOS ONE 9: e85692.
  • Zubrod, J.P., Jevtic, D.M., Melato, A.M., Englert, D., Weil, M., Brockmeier, E., Floehr, T., Knezevic, V., Agatz, A., Brinkmann, M. (2013) News from the SETAC Europe Student Advisory Council (April 2013) – the 3rd Young Environmental Scientists (YES) meeting at the Jagiellonian University, Poland. Environmental Sciences Europe 25: 16.
  • Hudjetz, S., Herrmann, H., Cofalla, C., Brinkmann, M., Kammann, U., Schäffer, A., Schüttrumpf, H., Hollert, H. (2013) An attempt to assess the relevance of flood events—biomarker response of rainbow trout exposed to resuspended natural sediments in an annular flume. Environmental Sciences and Pollution Research 21: 13744-13757.
  • Otte, J., Keiter, S., Faßbender, C., Higley, E.B., Suares Rocha, P., Brinkmann, M., Wahrendorf, D.-S., Manz, W., Wetzel, M.A., Braunbeck, T., Giesy, J.P., Hecker, M., Hollert, H. (2013) Contribution of Priority PAHs and POPs to Ah Receptor-Mediated Activities in Sediment Samples from the River Elbe Estuary, Germany. PLoS ONE 8: e75596.
  • Kammann, U., Brinkmann, M., Freese, M., Pohlmann, J.-D., Stoffels, S., Hollert, H., Hanel, R. (2013) PAH metabolites, GST and EROD in European eel (Anguilla anguilla) as possible indicators for eel habitat quality in German rivers. Environmental Sciences and Pollution Research 21: 2519-2530.
  • Eichbaum, K., Brinkmann, M., Buchinger, S., Hecker, M., Engwall, M., van Bavel, B., Reifferscheid, G., Hollert, H. (2013) The dioRAMA project: assessment of dioxin-like activity in sediments and fish (Rutilus rutilus) in support of the ecotoxicological characterization of sediments. Journal of Soils and Sediments 13: 770-774.
  • Brinkmann, M. & Hudjetz, S., Kuckelkorn, J., Yu, T., Cofalla, C., Roger, S., Kammann, U., Schüttrumpf, H., Hollert, H. (2013) How flood events affect rainbow trout: Evidence of a biomarker cascade in rainbow trout after exposure to PAH contaminated sediment suspensions. Aquatic Toxicology 128-129: 13-24.
  • Cofalla, C., Hudjetz, S., Roger, S., Brinkmann, M., Frings, R., Wölz, J., Schmidt, B., Schäffer, A., Kammann, U., Hecker, M., Hollert, H., Schüttrumpf, H. (2012) A combined hydraulic and toxicological approach to assess re-suspended sediments during simulated flood events—part II: an interdisciplinary experimental methodology. Journal of Soils and Sediments 12: 429-442.
  • Peddinghaus, S., Brinkmann, M., Bluhm, K., Sagner, A., Hinger, G., Braunbeck, T., Eisenträger, A., Tiehm, A., Hollert, H., Keiter, S. (2012) Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio). Reproductive Toxicology 33: 224-232.
  • Brinkmann, M., Hudjetz, S. Herrmann, H., Cofalla, C., Kammann, U., Hecker, M., Schüttrumpf, H., Schäffer, A., Hollert, H. (2012) Floodsearch: Hochwasser im Labormaßstab – Ökotoxikologie und Wasserbau arbeiten Hand in Hand bei der Hochwasserfolgenbewertung. Mitteilungen der GDCh Fachgruppe Umweltchemie und Ökotoxikologie, 4/2012.
  • Zubrod, J.P., Jevtic, D.M., Melato, A.M., Agatz, A., Englert, D., Floehr, T., Knezevic, V., Weil, M., Brinkmann, M. (2012) News from the SETAC Europe Student Advisory Council – September 2012. Environmental Sciences Europe 2012, 24: 27.
  • Brinkmann, M., Kaiser, D., Peddinghaus, S., Berens, M., Bräunig, J., Galic, N., Bundschuh, M., Zubrod, J.P., Dabrunz, A., Liu, T., Melato, M., Mieiro, C., Sdepanian, S., Westman, O., Kimmel, S., Seiler, T.-B. (2011) The Second Young Environmental Scientist (YES) meeting 2011 at RWTH Aachen University – environmental challenges in a changing world. Environmental Sciences Europe 23: 29.
  • Preuss, T.G., Brinkmann, M., Lundström, E., Chandler, T.G., Bengtsson, B.E., Breitholtz, M. (2011) An individual-based modeling approach for evaluation of endpoint sensitivity in harpacticoid copepod life-cycle tests and optimization of test design. Environmental Toxicology and Chemistry 30: 2353-2362.
  • Schüttrumpf, H., Brinkmann, M., Cofalla, C., Frings, R.M., Gerbersdorf, S.U., Hecker, M., Hudjetz, S., Kammann, U., Lennartz, G., Roger, S., Schäffer, A., Hollert, H. (2011) A new approach to investigate the interactions between sediment transport and ecotoxicological processes during flood events. Environmental Sciences Europe 2011, 23: 39.
  • Gerbersdorf, S.U., Hollert, H., Brinkmann, M., Wieprecht, S., Schüttrumpf, H., Manz, W. (2011) Anthropogenic pollutants affect ecosystem services of freshwater sediments: the need for a ‘triad plus x’ approach. Journal of Soils and Sediments 11: 1099-1114.
  • Hinger, G. & Brinkmann, M., Bluhm, K., Sagner, A., Takner, H., Eisenträger, A., Braunbeck, T., Engwall, M., Tiehm, A., Hollert, H. (2011) Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-CALUX assay and the EROD assay with RTL-W1 cells. Environmental Science and Pollution Research 18: 1297-1304.
  • Zielke, H., Seiler, T.-B., Niebergall, S., Leist, E., Brinkmann, M., Spira, D., Streck, G., Brack, W., Feiler, U., Braunbeck, T, Hollert, H. (2011) The impact of extraction methodologies on the toxicity of sediments in the zebrafish (Danio rerio) embryo test. Journal of Soils and Sediments 11: 352-363.
  • Cofalla, C., Roger, S., Frings, R.M., Schüttrumpf, H., Brinkmann, M., Hudjetz, S., Wölz, J., Hollert, H., Gerbersdorf, S.U., Hecker, M., Kammann, U., Lennartz, G., Schäffer, A. (2011) Eine Methode zur Bestimmung der Wechselwirkungen zwischen Sedimentdynamik und Ökotoxikologie. Hydrologie und Wasserwirtschaft 11: 227-230.
  • Brinkmann, M., Hallare, A.V., Hudjetz, S., Keiter, S., Seiler, T.-B., Wölz, J., Gerbersdorf, S.U., Cofalla, C., Roger, S., Schüttrumpf, H., Hollert, H. (2010) Toxicity and risk assessment of fluvial sediments and suspended matter: a short overview of past and recent developments in sediment toxicity assessment. Umweltwissenschaften und Schadstoffforschung 22: 651-655.
  • Brinkmann, M., Hudjetz, S., Cofalla, C., Roger, S., Kammann, U., Zhang, X., Wiseman, S., Giesy, J., Hecker, M., Schüttrumpf, H., Wölz, J., Hollert, H. (2010) A combined hydraulic and toxicological approach to assess re-suspended sediments during simulated flood events. Part I–multiple biomarkers in rainbow trout. Journal of Soils and Sediments 10: 1347–1361.
  • Brinkmann, M., Brooks, A., Dabrunz, A., Gomez-Eyles, J.L., Van Hoecke, K., Kienle, C., Seiler, T.-B., Bundschuh, M. (2010) SETAC Europe 19th annual meeting, Gothenburg, Sweden: next step towards fulfilling students’ needs – Meeting report by the Student Advisory Council (SAC) of SETAC Europe. Environmental Science and Pollution Research 17: 244-245.
  • Bundschuh, M., Zubrod, J.P., Galic, N., Dabrunz, A., Melato, M., Mieiro, C., Sdepanian, S., Westman, O., Liu, T., Kaiser, D., Brinkmann, M. (2010) 2nd SETAC Europe Young Environmental Scientists (YES) Meeting 2011 at RWTH Aachen University, 28 February till 2 March 2011. Umweltwissenschaften und Schadstoffforschung 22: 509–510.
  • Bundschuh, M., Dabrunz, A., Bollmohr, S., Brinkmann, M., Caduff, M., Gomez-Eyles, J.L., Kinele, C., Melato, M., Patrick-Iwuanyanwu, K.-C.P., Van Hoecke, K., Seiler, T.-B., Brooks, A. (2009) 1st Young Environmental Scientists (YES) Meeting—New challenges in environmental sciences. A meeting report by the Student Advisory Council of SETAC Europe. Environmental Science and Pollution Research 16: 479-481.
  • Brinkmann, M., Brooks, A., Dabrunz, A., Gomez-Eyles, J.L., Van Hoecke, K., Kienle, C., Seiler, T.-B., Bundschuh, M. (2009) SETAC Europe 19th annual meeting, Gothenburg, Sweden: next step towards fulfilling students’ needs – Meeting report by the Student Advisory Council (SAC) of SETAC. Umweltwissenschaften und Schadstoffforschung 21: 412-413.
  • Brinkmann, M., Dabrunz, A., Seiler, T.-B., Kienle, C., Bundschuh, M. (2009) 1st Young Environmental Scientists Meeting (YES-Meeting) – New Challenges in Environmental Sciences. Umweltwissenschaften und Schadstoffforschung 21: 113–114.
  • Schneider, A., Brinkmann, M., Gerstner, A., Wölz, J., Heger, S., Weber, R., Engwall, M., Seiler, T.-B., Hollert, H. (2009) Assessment of dioxin-like toxicity in soils contaminated by a chloralkali process and a leblanc factory. Organohalogen Compounds 71: 2278-2282.
  • Lundström, E., Brinkmann, M., Ek, K., Hollert, H., Persson, J.-O., Breitholtz, M. (2009) Comparison of six different treatment technologies – population level responses in the harpacticoid copepod Nitocra spinipes. Aquatic Toxicology 96: 298-307.
  • Wölz, J., Cofalla, C., Hudjetz, S., Roger, S., Brinkmann, M., Schmidt, B., Schäffer, A., Kammann, U., Lennartz, G., Hecker, M., Schüttrumpf, H. & Hollert, H. (2009) In search for the ecological and toxicological relevance of sediment re-mobilisation and transport during flood events. Journal of Soils and Sediments 9: 1-5.